WebAug 28, 2024 · Methods for treating cancers and precancerous conditions by administering an effective amount of a radiolabeled agent that targets cell surface phosphatidylserine, alone or in combination with other therapies, are provided. The radiolabeled phosphatidylserine targeting agent delivers radiation to cells that externally present … WebNov 1, 2009 · Circulating TSHR mRNA: TSHR mRNA in peripheral blood has been suggested as a potential molecular marker of circulating thyroid carcinoma cells to aid in the …
CoupledCARTM Technology for Treating Thyroid Cancer
WebPROBLEM TO BE SOLVED: To provide oxo-hydroquinazolines that are useful as selective thyroid stimulating hormone receptor (TSHR) agonists and may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder. SOLUTION: The present invention provides compounds represented by a formula in the figure. the posthuman
Entry - +603372 - THYROID-STIMULATING HORMONE RECEPTOR; …
WebThese agents are anticipated to be efficacious not only for the above-mentioned diseases but also for resistance to thyroid hormone and have utility for thyroid cancer radionuclide scintigraphy/therapy as a new theranostic. The thyrotropin receptor (TSHR) plays critical roles in thyroid growth and function and in the pathogenesis of several thyroid diseases … WebOncogenic mutations in BRAF are common in melanoma and thyroid carcinoma and drive constitutive ... which can differentiate papillary thyroid cancer (PTC) cell lines from a control thyroid cell line. An ... (TSHR and LSP1, respectively), confirmed the integrity of cell populations in the HT cohort. RNA was extracted ... WebThis specific binding behavior of TSHr with TSH can be adapted for generating a nanoparticle (NP) drug-delivery system to target thyroid cancer. 14,15 Indeed, liposomes … the posthuman child