WebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early … The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer … See more EEA1 is a RAB5A effector protein which binds via an N-terminal zinc finger domain and is required for fusion of early and late endosomes and for sorting at the early endosome level. See more Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole. Mycobacterium tuberculosis is known to inhibit the … See more • early+endosome+antigen+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural … See more • endosome • Phosphatidylinositol 3-phosphate • FYVE domain See more

EEA1 - Wikipedia

WebEea1 early endosome antigen 1 [ (house mouse)] Gene ID: 216238, updated on 8-Nov-2024 Summary Predicted to enable 1-phosphatidylinositol binding activity; GTP … WebEarly endosome antigen 1 (EEA1) is an early endosomal protein that contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for … chunli mod sf6

Anti-EEA1 antibody, Mouse monoclonal - Sigma-Aldrich

WebRab22a is an important small GTPase protein the molecule that is involved in intracellular transportation and regulation of proteins. It also plays an important role in antigens uptake, transportation, regulation of endosome morphology, and also regulates the transport of antigens to MHC (Major Histocompatibility Complex) molecules. To investigate the role … WebMar 8, 2024 · d LgBiT-FYVE and Early Endosome Antigen 1. In both cases, secondary antibodies coupled with oligonucleotides (PLA probes) bind to the primary antibodies. When the PLA probes are in close proximity ... WebEndosomes are found in three forms: early endosomes, late endosomes, and recycling endosomes. The early endosomes develop into late endosomes, which then fuse with … chun-li is worth it