Cisplatin 293t
WebJun 17, 1999 · Cisplatin requires MEKK1 for activation of JNK. 293T cells were transiently transfected with the indicated amounts of DNA encoding the wild-type or the dominant … Web将生长良好的细胞(Huh7、HepG2和293T细胞)筛选出来,其中293T细胞用来进行病毒包装,肝癌细胞Huh7和HepG2被用来进行细胞转染和后续细胞实验。 ... Promotion of cell death in cisplatin-resistant ovarian cancer cells through KDM1B-DCLRE1B modulation. Int J Mol Sci, 2024, 20(10): 2443. doi: 10.3390 ...
Cisplatin 293t
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WebCisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, … WebMay 11, 2016 · Since 293T was the embryonic kidney cells, the fast clearance or neutralizations could have made them resistant towards DXR. In conclusion, the same degree of sensitivity from the 2D system did not translate to a 3D culture system, resulting in higher IC50 values than the 2D system. ... Chen CL, Wang CK, et al. Cisplatin-, …
WebApr 8, 2024 · Glioma cell lines (U251, A172, U87, and T98G), 293T (HEK293T) cell line, and normal human astrocytes (NHA) were purchased from the China Center for Type Culture Collection (Shanghai, China). All the cells were cultured in DMEM medium (Gibco, CA, USA) containing 10% fetal bovine serum (FBS; Gibco, CA, USA) and 1% penicillin and … http://glycoenzymes.ccrc.uga.edu/MammalianExpression/MammalianTransfectionPEI.pdf
WebNov 25, 2024 · USP39 expression is correlated with the cisplatin chemosensitivity in colon cancer cell lines. a The level of USP39 detected by Western blotting in three colon cancer cells. b–d MTT assay was used to detect IC 50 values of HCT116, SW620, and RKO cells treated with cisplatin. e, g Western blotting analysis was employed to examine … WebJul 23, 2024 · Background: Breast cancer has one of highest morbidity and mortality rates for women. Abnormalities regarding epigenetics modification and pyruvate dehydrogenase kinase 1 (PDK1)-induced unusual metabolism contribute to breast cancer progression and chemotherapy resistance. However, the role and mechanism of epigenetic change in …
WebCisplatin is also used alone or in combination with other medications to treat bladder cancer that can not be treated with surgery or radiation therapy alone. Cisplatin is in a class of …
WebMar 15, 2024 · Background: Cisplatin is a highly effective chemotherapeutic agent commonly used in the treatment of a wide variety of malignancies. However, its clinical usage is severely limited by its serious side effects, especially nephrotoxicity. business partnership legal adviceWebMar 8, 2012 · Specifically, cell cycle analysis was performed with cisplatin-treated 293T, 293T/f-hMSH5, 293T/f-hMSH5 Y742F, and hMSH5-silenced 293T cells over a period of 72 hrs, in which the highest level of G2/M arrest occurred 24 … business partnership life insuranceWebSep 9, 2008 · The indicated PMS2 variants were each coexpressed with p73 or appropriate empty plasmid into 293T cells. Whole-cell lysates were used for immunoblotting after β-galactosidase activity normalization of transfection efficiency. ... Interaction of MLH1 with PMS2 or PMS2(R20Q) is not affected by cisplatin. 293T cells cotransfected with the ... business partnership life insurance policyWebCisplatin is a major anticancer drug that kills cancer cells by damaging their DNA. Cancer cells cope with the drug by removal of the damages with nucleotide excision repair. We … business partnership lawyerWebElectronic address: [email protected]. PMID: 29414646 DOI: 10.1016/j.intimp.2024.01.031 Abstract The present study assessed the possible therapeutic potential of a natural flavonoid morin hydrate (MH), against cisplatin (CP) induced toxicity in HEK-293 cells and mice kidney. business partnership objectivesWebDec 12, 2024 · Cisplatin (CP) is an effective chemotherapeutic agent widely used in the treatment of various solid tumours. However, CP nephrotoxicity is an important limitation for CP use; currently, there is... business partnership messageWebWe conclude that PJ34 significantly suppresses HepG2 cell growth in a dose-dependent manner, and inhibits HepG2 cell-derived tumor growth in nude mice. The suppressive effects of PJ34 are associated with increased cell apoptosis. Furthermore, PJ34 enhances suppressive effects of cisplatin in HepG2 cells. business partnership invitation letter